Faculty Positions
Laboratory of Medical Genetics
Harbin Medical University

The Harbin Medical University, Laboratory of Medical Genetics is seeking outstanding scientists for two RESEARCH ASSOCIATE positions. Applicants should be highly motivated M.D. and/or Ph.D. who have a sound record of research and publications in the areas of human genetics and computational genetics, especially in bioinformatics analysis of genomics and proteomics data. You will join a team of researchers interested in the Structure and Function of Double Minute Chromosomes (DMs) and the Diversity Research in Different Human Populations (see http://www.hmugenet.com). Application together with a curriculum vitae and a list of publications, should be returned via email to:

Songbin Fu, M.D.,Ph.D.
Vice President of Harbin Medical University
Dean of Medical Genetics Laboratory
Harbin Medical University
Harbin 150081, China
Email: fusb@ems.hrbmu.edu.cn, fusongbin@yahoo.com

Laboratory of Medical Genetics, Harbin Medical University
Job Title: Postdoctoral Research Associate
Date Posted:  08/22/2008
Application Deadline: Open Until Filled
  
Job Description
Two Postdoctoral Associate positions are available immediately for motivated scientists with Ph.D. or M.D. degree and a strong background in human genetics and computational genetics, especially in bioinformatics analysis of genomics and proteomics data..One project is structural and functional research on Double minute chromosomes (DMs), which will study the functional role of DMs in the cancer genesis and progression. Microdissection technology is applied to separate the double minute chromosomes (DMs) in tumor cells for the subsequent cloning and sequencing of DMs. The other project is  genetic resource preservation and diversity research in different populations of China. Chinese human genetic resource bank-the Harbin Bank as well as preservation of precious genetic samples of 56 populations in China, the special populations, the diseased and its corresponding control populations have been successfully established using the method of Epstein Barr virus transformation of human B lymphoblastoid cells.  Detailed information can be got through http://www.hmugenet.com/en/index.asp.
These projects are all funded on separate “National Natural Science Foundation of China” grants.
These positions are especially recommended to Science & Technology Fellowship Programme in China (STF CHINA), and are for 2 years with starting date as early as March 1st, 2009.

Relevant Publications:
Yihui Fan, Renfang Mao, Jing Bai, Xiaohong Zhang, Qingquan Lei, Songbin Fu. AFM images of G1-phase premature condensed chromosomes:Evidence for 30 nm changed to 50 nm chromatin fibers. Applied Surface Science, 2008, 254:1676–1683
Renfang Mao, Yihui Fan, Feng Chen and Songbin Fu.Genetic polymorphism of MTHFR G1793A in Chinese populations. Eur J Epidemiol, 2008, 23:363–368
Yihui Fan, Xiaohong Zhang, Jing Bai, Renfang Mao, Chunyu Zhang, Qingquan Lei, Songbin Fu. Ultrastructural organization of premature condensed chromosomes at S-phase as observed by atomic force microscopy. Applied Surface Science, 2007, 253(12): 5281-5286.
Yali Xue，Tatiana Zerjal，Weidong Bao, Suling Zhu，Qunfang Sun, Jiujin Xu，Ruofu Du，Songbin Fu，Pu Li，Matthew E. Hurles, Huanming Yang, and Chris Tyler-Smith. Male Demography in East Asia: A North–South Contrast in Human Population Expansion Times. Genetics, 2006, 172: 2431–2439
X. L. Zhang, C. Y. Zhang, Y. Yu, F. Chen, P. Li & S. B. Fu. CCR2 allele polymorphisms in 15 Chinese ethnic populations. International Journal of Immunogenetics, 2006, 33:45-48
Chun-yu Zhang, Yuan-xi Feng, Yang Yu, Wen-jing Sun, Jing Bai, Feng Chen and Song-bin Fu. The molecular mechanism of resistance to methotrexate in mouse methotrexate-resistant cells by cancer drug resistance and metabolism SuperArray. Basic Clin Pharmacol Toxicol, 2006, 99(2): 141-145.
Xinyu Deng, Liangyu Zhang, Yu Zhang, Yongda Yan, Zongwei Xu, Shen Dong, and Songbin Fu. Double minute chromosomes in mouse methotrexate-resistant cells studied by atomic force microscopy. Biochem Biophys Res Commun, 2006, 346(4): 1228-33.
Yali Xue, Tatiana Zerjal, Weidong Bao, Suling Zhu, Si-Keun Lim, Qunfang Shu, Jiujin Xu, Ruofu Du, Songbin Fu, Pu Li, Huanming Yang, Chris Tyler-Smith. Recent Spread of a Y-Chromosomal Lineage in Northern China and Mongolia. Am. J. Hum. Genet., 2005, 77:1112-6

Interested candidates should send a CV and names of references to:
Songbin Fu, M.D.,Ph.D.
Vice President of Harbin Medical University
Dean of Medical Genetics Laboratory
Harbin Medical University
Harbin 150081, China
Email: fusb@ems.hrbmu.edu.cn, fusongbin@yahoo.com